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Vascular Neoplasm

MedGen UID:: 10299
•Concept ID:: C0027668
•: Neoplastic Process

Synonyms:

Neoplasm, Vascular Tissue; Neoplasms, Vascular Tissue; Vascular Tissue Neoplasm; Vascular Tissue Neoplasms

Definition

A benign, intermediate, or malignant neoplasm arising from vascular tissue including arteries, veins, venous sinuses, lymphatic vessels, arterioles and capillaries. It may occur in essentially any body location and is characterized by the presence of vascular channel formation and endothelial cells. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVVascular Neoplasm

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Disorder of cardiovascular system
        Cardiovascular neoplasm
        Vascular Neoplasm
        Angiofibromas
        Angiofibroma of Soft Tissue
        Cellular Angiofibroma
        Paratesticular Cellular Angiofibroma
        Vulvar Cellular Angiofibroma
        Giant Cell Angiofibroma
        Gingival Angiofibroma
        Juvenile nasopharyngeal angiofibroma
        Angiokeratoma
        Angiokeratoma circumscriptum naeviforme
        Angiokeratoma of Fordyce
        Angiokeratoma of mibelli
        Fabry disease
        Skin Angiokeratoma
        Angiokeratoma circumscriptum
        Solitary angiokeratoma
        Vulvar angiokeratoma
        Angiosarcoma
        Adult Angiosarcoma
        Angiosarcoma Associated with Lymphedema
        Angiosarcoma of the Skin of the Arm after Radical Mastectomy followed by Lymphedema
        Angiosarcoma NCI Grade 2
        Angiosarcoma NCI Grade 3
        Bone angiosarcoma
        Conjunctival Angiosarcoma
        Conventional angiosarcoma
        Localized Angiosarcoma
        Metastatic angiosarcoma
        Advanced Angiosarcoma
        Locally Advanced Angiosarcoma
        Pediatric angiosarcoma
        Poorly Differentiated Angiosarcoma
        Radiation-Related Angiosarcoma
        Skin Radiation-Related Angiosarcoma
        Recurrent Angiosarcoma
        Recurrent Breast Angiosarcoma
        Recurrent Skin Angiosarcoma
        Soft Tissue Angiosarcoma
        Breast angiosarcoma
        Central nervous system angiosarcoma
        Penile Angiosarcoma
        Peripheral Intraneural Angiosarcoma
        Sinonasal Angiosarcoma
        Skin angiosarcoma
        Visceral Angiosarcoma
        Vulvar Angiosarcoma
        Unresectable Angiosarcoma
        Benign vascular tumor
        Benign blood vessel neoplasm
        Angiomatosis
        Hemangioma
        Benign Lymphatic Vessel Neoplasm
        Lymphangioma
        Benign Skin Vascular Neoplasm
        Skin hemangioma
        Skin lymphangioma
        Benign Thyroid Gland Vascular Neoplasm
        Thyroid Gland Hemangioma
        Thyroid Gland Lymphangioma
        Blood vessel neoplasm
        Hemangioendothelioma
        Composite hemangioendothelioma
        Epithelioid hemangioendothelioma
        Kaposiform hemangioendothelioma
        Polymorphus Hemangioendothelioma
        Primary intralymphatic angioendothelioma
        Retiform hemangioendothelioma
        Skin Hemangioendothelioma
        Intermediate Blood Vessel Neoplasm
        Intermediate (Locally Aggressive) Blood Vessel Neoplasm
        Intermediate (Rarely Metastasizing) Blood Vessel Neoplasm
        Vascular cancer
        Kaposi sarcoma
        Breast Vascular Neoplasm
        Breast angiomatosis
        Breast hemangioma
        Breast capillary hemangioma
        Breast epithelioid hemangioma
        Glomus tumor
        Benign Glomus Tumor
        Glomangiomatosis
        Bone Glomus Tumor
        Gastric Glomus Tumor
        Glomangioma
        Cutaneous glomangioma
        Hereditary Glomangioma
        Glomangiomyoma
        Glomus Tumor of Uncertain Malignant Potential
        Malignant glomus tumor
        Metastatic Malignant Glomus Tumor
        Refractory Malignant Glomus Tumor
        Unresectable Malignant Glomus Tumor
        Penile Glomus Tumor
        Skin glomus tumor
        Subungual glomus tumor
        Solid Glomus Tumor
        Hemangiopericytoma
        Benign Hemangiopericytoma
        Benign Kidney Hemangiopericytoma
        Benign Mediastinal Hemangiopericytoma
        Benign Orbit Hemangiopericytoma
        Infantile Hemangiopericytoma
        Lipomatous Hemangiopericytoma
        Breast hemangiopericytoma
        Hemangiopericytoma of skin
        Malignant Skin Hemangiopericytoma
        Hemangiopericytoma, malignant
        Adult malignant hemangiopericytoma
        Childhood malignant hemangiopericytoma
        Conventional malignant hemangiopericytoma
        Heart malignant hemangiopericytoma
        Malignant mediastinum hemangiopericytoma
        Malignant Orbit Hemangiopericytoma
        Metastatic Malignant Hemangiopericytoma
        Primary Malignant Hemangiopericytoma
        Recurrent Malignant Hemangiopericytoma
        Well Differentiated Malignant Hemangiopericytoma
        Kidney Solitary Fibrous Tumor
        Myopericytoma
        Orbit Hemangiopericytoma
        Retroperitoneal hemangiopericytoma
        Intermediate Vascular Neoplasm
        Lymphatic vessel neoplasm
        Lymphangiomatosis
        Diffuse Pulmonary Lymphangiomatosis
        Liver Lymphangiomatosis
        Lymphangiomyoma
        Lymphangiomyomatosis
        Lymphangiosarcoma
        Skin lymphangiosarcoma
        Malignant Vascular Neoplasm
        Malignant Skin Vascular Neoplasm
        Skin Kaposi Sarcoma
        Meningioma
        Adult Meningioma
        Adult Grade 1 Meningioma
        Adult Grade 2 Meningioma
        Adult Grade 3 Meningioma
        Adult Intracranial Meningioma
        Deletion of Chromosome 22 Associated Meningioma
        Deletion of Chromosome 3p Associated Meningioma
        Deletion of the Short Arm of Chromosome 1 (1p) Associated Meningioma
        Grade 1 Meningioma
        Angiomatous meningioma
        Benign meningioma
        Childhood Grade 1 Meningioma
        Fibrous meningioma
        Lymphoplasmacyte-rich meningioma
        Meningothelial meningioma
        Metaplastic Meningioma
        Microcystic meningioma
        Psammomatous meningioma
        Secretory meningioma
        Transitional meningioma
        Grade II meningioma
        Atypical Meningioma
        Childhood Grade 2 Meningioma
        Chordoid meningioma
        Clear cell meningioma
        Grade III meningioma
        Anaplastic meningioma
        Childhood Grade 3 Meningioma
        Papillary meningioma
        Rhabdoid meningioma
        Hereditary Meningioma
        Intracranial meningioma
        Anaplastic (Malignant) Intracranial Meningioma
        Benign Intracranial Meningioma
        Childhood brain meningioma
        Choroid plexus meningioma
        Intraventricular meningioma
        Optic tract meningioma
        Papillary meningioma of the cerebellum
        Radiation-Induced Intracranial Meningioma
        Skull base meningioma
        Supratentorial meningioma
        Meningioma by Site
        Intraorbital meningioma
        Intraspinal meningioma
        Jugular foramen meningioma
        Metastatic Meningioma
        Multiple meningiomas
        Multiple skull base meningioma
        Multiple spinal canal and spinal cord meningioma
        Optic nerve sheath meningioma
        Pediatric meningioma
        Recurrent Meningioma
        Recurrent Anaplastic (Malignant) Meningioma
        Recurrent Atypical Meningioma
        Refractory Meningioma
        Spinal meningioma
        Unresectable Meningioma
        Skin Vascular Neoplasm
        Vascular bone neoplasm
        Bone Epithelioid Hemangioendothelioma
        Bone Hemangioma
        Bone epithelioid hemangioma

Professional guidelines

PubMed

Management Strategies for Patients With Epithelioid Hemangioendothelioma: Charting an Indolent Disease Course.

Yurkiewicz IR, Zhou M, Ganjoo KN, Charville GW, Bolleddu S, Lohman M, Bui N
Am J Clin Oncol 2021 Aug 1;44(8):419-422. doi: 10.1097/COC.0000000000000827. PMID: 34028371

Ulnar tunnel syndrome: pathoanatomy, clinical features and management.

Scarborough A, MacFarlane RJ, Mehta N, Smith GD
Br J Hosp Med (Lond) 2020 Sep 2;81(9):1-9. Epub 2020 Sep 25 doi: 10.12968/hmed.2020.0298. PMID: 32990073

Primary Hepatic Neoplasms of Vascular Origin: Key Imaging Features and Differential Diagnoses With Radiology-Pathology Correlation.

Choi HH, Manning MA, Mehrotra AK, Wagner S, Jha RC
AJR Am J Roentgenol 2017 Dec;209(6):W350-W359. Epub 2017 Oct 12 doi: 10.2214/AJR.17.18100. PMID: 29023152

See all (11)

Recent clinical studies

Etiology

A unique epithelioid vascular neoplasm of bone characterized by EWSR1/FUS-NFATC1/2 fusions.

Dashti NK, Dickson BC, Zhang L, Xie Z, Nielsen GP, Antonescu CR
Genes Chromosomes Cancer 2021 Nov;60(11):762-771. Epub 2021 Aug 6 doi: 10.1002/gcc.22984. PMID: 34310785 Free PMC Article

Kaposiform hemangioendothelioma: current knowledge and future perspectives.

Ji Y, Chen S, Yang K, Xia C, Li L
Orphanet J Rare Dis 2020 Feb 3;15(1):39. doi: 10.1186/s13023-020-1320-1. PMID: 32014025 Free PMC Article

Radiation-induced angiosarcoma of the breast: A review.

Bonito FJP, de Almeida Cerejeira D, Dahlstedt-Ferreira C, Oliveira Coelho H, Rosas R
Breast J 2020 Mar;26(3):458-463. Epub 2019 Aug 25 doi: 10.1111/tbj.13504. PMID: 31448482

Angiolymphoid hyperplasia with eosinophilia and Kimura's disease - a clinical and histopathological comparison.

Buder K, Ruppert S, Trautmann A, Bröcker EB, Goebeler M, Kerstan A
J Dtsch Dermatol Ges 2014 Mar;12(3):224-8. doi: 10.1111/ddg.12257_suppl. PMID: 24580875

Pyogenic granuloma in children.

Pagliai KA, Cohen BA
Pediatr Dermatol 2004 Jan-Feb;21(1):10-3. doi: 10.1111/j.0736-8046.2004.21102.x. PMID: 14871318

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Diagnosis

Atypical presentation of cutaneous meningioma.

Chen A, Hall M, Liu W, Arps D
J Cutan Pathol 2023 Feb;50(2):110-112. Epub 2022 Sep 14 doi: 10.1111/cup.14316. PMID: 35996326

Kaposiform hemangioendothelioma: current knowledge and future perspectives.

Ji Y, Chen S, Yang K, Xia C, Li L
Orphanet J Rare Dis 2020 Feb 3;15(1):39. doi: 10.1186/s13023-020-1320-1. PMID: 32014025 Free PMC Article

Radiation-induced angiosarcoma of the breast: A review.

Bonito FJP, de Almeida Cerejeira D, Dahlstedt-Ferreira C, Oliveira Coelho H, Rosas R
Breast J 2020 Mar;26(3):458-463. Epub 2019 Aug 25 doi: 10.1111/tbj.13504. PMID: 31448482

Kaposiform hemangioendothelioma.

Fernández Y, Bernabeu-Wittel M, García-Morillo JS
Eur J Intern Med 2009 Mar;20(2):106-13. Epub 2008 Aug 15 doi: 10.1016/j.ejim.2008.06.008. PMID: 19327597

Imaging of tinnitus: a review.

Weissman JL, Hirsch BE
Radiology 2000 Aug;216(2):342-9. doi: 10.1148/radiology.216.2.r00au45342. PMID: 10924551

See all (300)

Therapy

Infantile Hemangiomas.

Hasbani DJ, Hamie L
Dermatol Clin 2022 Oct;40(4):383-392. Epub 2022 Sep 16 doi: 10.1016/j.det.2022.06.004. PMID: 36243426

Management Strategies for Patients With Epithelioid Hemangioendothelioma: Charting an Indolent Disease Course.

Yurkiewicz IR, Zhou M, Ganjoo KN, Charville GW, Bolleddu S, Lohman M, Bui N
Am J Clin Oncol 2021 Aug 1;44(8):419-422. doi: 10.1097/COC.0000000000000827. PMID: 34028371

Everolimus for Treatment of Pseudomyogenic Hemangioendothelioma.

Ozeki M, Nozawa A, Kanda K, Hori T, Nagano A, Shimada A, Miyazaki T, Fukao T
J Pediatr Hematol Oncol 2017 Aug;39(6):e328-e331. doi: 10.1097/MPH.0000000000000778. PMID: 28121744

Pyogenic granuloma of the lip - treatment with carbon dioxide slush cryosurgery as an approach in a resource-poor country.

Al-Qubati Y, Janniger EJ, Schwartz RA
Adv Clin Exp Med 2014 Jan-Feb;23(1):5-7. doi: 10.17219/acem/37009. PMID: 24595997

Signaling pathways in the development of infantile hemangioma.

Ji Y, Chen S, Li K, Li L, Xu C, Xiang B
J Hematol Oncol 2014 Jan 31;7:13. doi: 10.1186/1756-8722-7-13. PMID: 24479731 Free PMC Article

See all (48)

Prognosis

Proposed diagnostic and prognostic markers of primary malignant hepatic vascular neoplasms.

Yoo Y, Shin J, Jun E, Koh EY, Shin HJ, Kang HJ
Diagn Pathol 2024 May 13;19(1):68. doi: 10.1186/s13000-024-01482-5. PMID: 38741104 Free PMC Article

Anastomosing hemangioma: a current update on clinical, pathological and imaging features.

Shanbhogue K, Khandelwal A, Hajdu C, Cao W, Surabhi VR, Prasad SR
Abdom Radiol (NY) 2022 Jul;47(7):2335-2346. Epub 2022 Jun 9 doi: 10.1007/s00261-022-03559-5. PMID: 35678844

Unilateral swelling and hyperpigmented papules.

Ajayi A, Sokumbi O
Dermatol Online J 2021 Dec 15;27(12) doi: 10.5070/D3271256716. PMID: 35499446

Radiation-induced angiosarcoma of the breast: A review.

Bonito FJP, de Almeida Cerejeira D, Dahlstedt-Ferreira C, Oliveira Coelho H, Rosas R
Breast J 2020 Mar;26(3):458-463. Epub 2019 Aug 25 doi: 10.1111/tbj.13504. PMID: 31448482

Terminal Bleeding in Angiosarcoma.

Gill JM, Madden B, Frost J, Crane-Okada R, Hulsman RL, Elliott K, Saria MG
J Palliat Med 2019 Aug;22(8):1009-1013. Epub 2019 Mar 13 doi: 10.1089/jpm.2018.0466. PMID: 30864873

See all (117)

Clinical prediction guides

Propranolol for the treatment of infantile hemangiomas: a nine-year monocentric experience from a tertiary hospital.

Volonté M, Codazzi AC, Davidovich S, Apicella A, Isoletta E, Barruscotti S, Massa M, Silvestri A, Marseglia GL, Brazzelli V
Eur J Dermatol 2023 Jun 1;33(3):265-269. doi: 10.1684/ejd.2023.4484. PMID: 37594334

Epithelioid Hemangioendothelioma in the Tongue: A Rare Case Report.

Cirkin DS, Secinti IE, Dogan E, Ozler GS
Turk Patoloji Derg 2023;39(1):94-97. doi: 10.5146/tjpath.2021.01560. PMID: 34757619 Free PMC Article

Tumor microenvironment and its clinicopathological and prognostic associations in surgically resected cutaneous angiosarcoma.

Bi Y, Ge L, Ren X, Pang J, Zhao Y, Liang Z
Clin Transl Oncol 2022 May;24(5):941-949. Epub 2022 Jan 22 doi: 10.1007/s12094-021-02744-0. PMID: 35064455

Hemangioblastoma: An Unsuspected Pitfall in PSMA PET/CT.

Gohimont N, Jissendi Tchofo P, Racu ML, Entezari K, Salmon I, Tondeur M, Ene D
Clin Nucl Med 2021 Jun 1;46(6):485-487. doi: 10.1097/RLU.0000000000003511. PMID: 33492863

Hepatic small vessel neoplasm, a rare infiltrative vascular neoplasm of uncertain malignant potential.

Gill RM, Buelow B, Mather C, Joseph NM, Alves V, Brunt EM, Liu TC, Makhlouf H, Marginean C, Nalbantoglu I, Sempoux C, Snover DC, Thung SN, Yeh MM, Ferrell LD
Hum Pathol 2016 Aug;54:143-51. Epub 2016 Apr 14 doi: 10.1016/j.humpath.2016.03.018. PMID: 27090685 Free PMC Article

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Recent systematic reviews

Pediatric Intranasal Lobular Capillary Hemangioma: A Scoping Review and Multimedia Case Presentation.

Valencia-Sanchez BA, Shokri T, Kalmar CL, Patel VA
Ann Plast Surg 2024 Nov 1;93(5):637-642. Epub 2024 Sep 3 doi: 10.1097/SAP.0000000000004094. PMID: 39227566

See all (1)

MedGen

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Vascular Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Recent activity